MAOIs are known as monoamine oxidase inhibitors that belong to a group of medicines to improve diverse depression types. The remedies were first used in the 1950s and had been actively used as depression treatments for many years. Although the development of the pharmaceutical sphere led to the production of other medicines to treat the conditions that drove MAOIs out, lots of patients still benefits from their use.
Action of the Medication and Its Impact on the Organism
Irrespective of type and form, MAO inhibitors produce a drastic effect on the organism. The medications work with brain chemicals called neurotransmitters that enable intercommunication of the brain cells. When the levels of the chemicals (including norepinephrine, dopamine and serotonin) fall, a person experiences the state that is called depression. Monoamine oxidase, chemical produced in the organism, removes these neurotransmitters causing their lack, thus, low spirits. Inhibiting the chemical, MAOIs increase the number of neurotransmitters left in the body, improving the mood.
Widely Spread Types of MAO Inhibitors
Even though the popularity and demand of MAO inhibitors is comparatively small, the medications are still potent to treat depression. They are also approved by the Food and Drug Administration as prescription drugs. The treatment course may range from 3 to 6 weeks, so that after this you are sure to get the desired effects. MAO inhibitors can be of four types such as:
- Tranylcypromine can be bought under the name of Pernate;
- Isocarboxazid, sold as Marplan;
- Phenelzine can be purchased as Nardi;
- Selegiline is known on the pharmaceutical market as Eldepryl, Zelapar and Emsam.
MAOIs Precautions, Side Effects and Recommendations
Before the beginning of MAOIs treatment course, it is inevitable to consult a doctor and get a prescription. These medications interact with a great number of other drugs, vitamins, supplements and even usual products. Thus, to avoid possible complications, one should avoid cured or aged meat, cheese, soy products, etc.
Besides, it is essential to keep in mind the negative drug interactions that may occur. Never take MAOIs with other antidepressants and herbal supplements without doctor’s permission. Do not begin another treatment course within two weeks after MAOIs intake.
Despite an impressive effect the medication produces on the body, the number of potential side effects is enormous. That contributes to the fact the drugs are often the last medication recommended for depression treatment. As any other antidepressants, MAO inhibitors cause such minor downsides as headache, weariness, nervousness, insomnia, etc. Though, apart from these insignificant symptoms, the pharmaceuticals may lead to low libido and erectile dysfunction, diarrhea, severe stomach disorders, sudden weight gain, increased blood pressure, dry mouth, muscle aches, lightheadedness and others.
Nowadays you can buy any MAO inhibitor as well as other necessary medications at Canadian Pharmacy and benefit from great prices and convenient services this online drugstore offers.